About Protein YIF1A
Protein YIF1A (YIF1A) is a protein
from Homo sapiens identified by UniProt accession
O95070, 293 residues long.
MolForge cross-references it against 0 known binders and
20 disease associations.
Target properties
| Protein name | Protein YIF1A |
|---|
| UniProt accession | O95070 |
|---|
| Gene | YIF1A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 293 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (20)
Diseases linked to this target (Open Targets).
- isolated asymptomatic elevation of creatine phosphokinase · score 0.07
- Immature Reticulocyte Fraction Measurement · score 0.06
- mean reticulocyte volume · score 0.06
- pentosuria · score 0.05
- bipolar disorder · score 0.04
- bladder transitional cell carcinoma · score 0.03
- urate measurement · score 0.02
- mean platelet volume · score 0.02
- ovarian carcinoma · score 0.01
- oligodendroglioma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95070-F1 | alphafold | PREDICTED | 73.61 | — |
Amino-acid sequence (293 residues)
MAYHSGYGAH GSKHRARAAP DPPPLFDDTS GGYSSQPGGY PATGADVAFS VNHLLGDPMA NVAMAYGSSI ASHGKDMVHK ELHRFVSVSK LKYFFAVDTA YVAKKLGLLV FPYTHQNWEV QYSRDAPLPP RQDLNAPDLY IPTMAFITYV LLAGMALGIQ KRFSPEVLGL CASTALVWVV MEVLALLLGL YLATVRSDLS TFHLLAYSGY KYVGMILSVL TGLLFGSDGY YVALAWTSSA LMYFIVRSLR TAALGPDSMG GPVPRQRLQL YLTLGAAAFQ PLIIYWLTFH LVR
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