About Neurexophilin-2
Neurexophilin-2 (NXPH2) is a protein
from Homo sapiens identified by UniProt accession
O95156, 264 residues long.
MolForge cross-references it against 0 known binders and
20 disease associations.
Target properties
| Protein name | Neurexophilin-2 |
|---|
| UniProt accession | O95156 |
|---|
| Gene | NXPH2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 264 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (20)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.40
- pregnancy induced alloimmunization · score 0.31
- multiple sclerosis · score 0.03
- clear cell renal carcinoma · score 0.01
- uterine leiomyosarcoma · score 0.01
- IGA glomerulonephritis · score 0.01
- pancreatic ductal adenocarcinoma · score 0.01
- Kidney Oncocytoma · score 0.00
- infect · score 0.00
- infection · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95156-F1 | alphafold | PREDICTED | 67.65 | — |
Amino-acid sequence (264 residues)
MRLRPLPLVV VPGLLQLLFC DSKEVVHATE GLDWEDKDAP GTLVGNVVHS RIISPLRLFV KQSPVPKPGP MAYADSMENF WDWLANITEI QEPLARTKRR PIVKTGKFKK MFGWGDFHSN IKTVKLNLLI TGKIVDHGNG TFSVYFRHNS TGLGNVSVSL VPPSKVVEFE VSPQSTLETK ESKSFNCRIE YEKTDRAKKT ALCNFDPSKI CYQEQTQSHV SWLCSKPFKV ICIYIAFYSV DYKLVQKVCP DYNYHSETPY LSSG
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