About Neurexophilin-3
Neurexophilin-3 (NXPH3) is a protein
from Homo sapiens identified by UniProt accession
O95157, 252 residues long.
MolForge cross-references it against 0 known binders and
19 disease associations.
Target properties
| Protein name | Neurexophilin-3 |
|---|
| UniProt accession | O95157 |
|---|
| Gene | NXPH3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 252 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (19)
Diseases linked to this target (Open Targets).
- mean corpuscular hemoglobin · score 0.23
- mean corpuscular volume · score 0.08
- heel bone mineral density · score 0.06
- erythrocyte count · score 0.05
- neoplasm · score 0.03
- non-small cell lung carcinoma · score 0.02
- colorectal cancer · score 0.02
- myxosarcoma · score 0.02
- endometrial carcinoma · score 0.01
- telomere syndrome · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95157-F1 | alphafold | PREDICTED | 71.93 | — |
Amino-acid sequence (252 residues)
MQLTRCCFVF LVQGSLYLVI CGQDDGPPGS EDPERDDHEG QPRPRVPRKR GHISPKSRPM ANSTLLGLLA PPGEAWGILG QPPNRPNHSP PPSAKVKKIF GWGDFYSNIK TVALNLLVTG KIVDHGNGTF SVHFQHNATG QGNISISLVP PSKAVEFHQE QQIFIEAKAS KIFNCRMEWE KVERGRRTSL CTHDPAKICS RDHAQSSATW SCSQPFKVVC VYIAFYSTDY RLVQKVCPDY NYHSDTPYYP SG
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