About Sciellin
Sciellin (SCEL) is a protein
from Homo sapiens identified by UniProt accession
O95171, 688 residues long.
MolForge cross-references it against 0 known binders and
66 disease associations.
Target properties
| Protein name | Sciellin |
|---|
| UniProt accession | O95171 |
|---|
| Gene | SCEL |
|---|
| Organism | Homo sapiens |
|---|
| Length | 688 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (66)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.40
- hair colour measurement · score 0.34
- protein measurement · score 0.32
- waist-hip ratio · score 0.29
- Other immunodeficiency syndrome with predominantly antibody defects · score 0.25
- serum gamma-glutamyl transferase measurement · score 0.10
- triple-negative breast cancer · score 0.07
- neoplasm · score 0.06
- lymphocyte count · score 0.06
- hair color · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95171-F1 | alphafold | PREDICTED | 45.24 | — |
Amino-acid sequence (688 residues)
MSNVTLRKMS PTGNEMKSTT QGTTRKQQDF HEVNKRRTFL QDNSWIKKRP EEEKDENYGR VVLNRHNSHD ALDRKVNERD VPKATISRYS SDDTLDRISD RNDAAKTYKA NTLDNQLTNR SMSMFRSLEV TKLQPGGSLN ANTSNTIAST SATTPVKKKR QSWFPPPPPG YNASSSTGTR RREPGVHPPI PPKPSSPVSS PNQLRQDNRQ IHPPKPGVYT ETNRSAERNI RSQDLDNIVK VATSLQRSDK GEELDNLIKM NKSLNRNQGL DSLFRANPKV EEREKRAKSL ESLIYMSTRT DKDGKGIQSL GSPIKVNQRT DKNEKGRQNL ESVAKVNARM NKTSRRSEDL DNATEVNPKG HENTTGKKDL DGLIKVDPET NKNITRGQSL DNLIKVTPEV KRSNQGSKDL NNFIKVYPGT EKSTEGGQSL DSLIKVTPER NRTNQGNQDL ENLIKVIPSA NKSSEQGLDE HINVSPKAVK NTDGKQDLDK LIKVNPEIFT NNQRNQDLAN LIKVNPAVIR NNQSQDLDNL IKVKPSALRN TNRDQNLENL IEVNSHVSEN KNGSSNTGAK QAGPQDTVVY TRTYVENSKS PKDGYQENIS GKYIQTVYST SDRSVIERDM CTYCRKPLGV ETKMILDELQ ICCHSTCFKC EICKQPLENL QAGDSIWIYR QTIHCEPCYS KIMAKWIP
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