About Ornithine decarboxylase antizyme 2
Ornithine decarboxylase antizyme 2 (OAZ2) is a protein
from Homo sapiens identified by UniProt accession
O95190, 189 residues long.
MolForge cross-references it against 0 known binders and
51 disease associations.
Target properties
| Protein name | Ornithine decarboxylase antizyme 2 |
|---|
| UniProt accession | O95190 |
|---|
| Gene | OAZ2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 189 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (51)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- neuroinflammatory disorder · score 0.37
- platelet count · score 0.16
- PR interval · score 0.11
- mean platelet volume · score 0.10
- age at menarche · score 0.09
- mean corpuscular hemoglobin concentration · score 0.08
- insulin like growth factor measurement · score 0.08
- coronary artery disease · score 0.08
- mean corpuscular volume · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95190-F1 | alphafold | PREDICTED | 77.17 | — |
Amino-acid sequence (189 residues)
MINTQDSSIL PLSNCPQLQC CRHIVPGPLW CSDAPHPLSK IPGGRGGGRD PSLSALIYKD EKLTVTQDLP VNDGKPHIVH FQYEVTEVKV SSWDAVLSSQ SLFVEIPDGL LADGSKEGLL ALLEFAEEKM KVNYVFICFR KGREDRAPLL KTFSFLGFEI VRPGHPCVPS RPDVMFMVYP LDQNLSDED
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