About Transcriptional repressor RHIT
Transcriptional repressor RHIT (ZNF205) is a protein
from Homo sapiens identified by UniProt accession
O95201, 554 residues long.
MolForge cross-references it against 0 known binders and
36 disease associations.
Target properties
| Protein name | Transcriptional repressor RHIT |
|---|
| UniProt accession | O95201 |
|---|
| Gene | ZNF205 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 554 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95201-F1 | alphafold | PREDICTED | 62.46 | — |
Amino-acid sequence (554 residues)
MSADGGGIQD TQDKETPPEV PDRGHPHQEM PSKLGEAVPS GDTQESLHIK MEPEEPHSEG ASQEDGAQGA WGWAPLSHGS KEKALFLPGG ALPSPRIPVL SREGRTRDRQ MAAALLTAWS QMPVTFEDVA LYLSREEWGR LDHTQQNFYR DVLQKKNGLS LGFPFSRPFW APQAHGKGEA SGSSRQAGDE KEWRGACTGA VEVGQRVQTS SVAALGNVKP FRTRAGRVQW GVPQCAQEAA CGRSSGPAKD SGQPAEPDRT PDAAPPDPSP TEPQEYRVPE KPNEEEKGAP ESGEEGLAPD SEVGRKSYRC EQCGKGFSWH SHLVTHRRTH TGEKPYACTD CGKRFGRSSH LIQHQIIHTG EKPYTCPACR KSFSHHSTLI QHQRIHTGEK PYVCDRCAKR FTRRSDLVTH QGTHTGAKPH KCPICAKCFT QSSALVTHQR THTGVKPYPC PECGKCFSQR SNLIAHNRTH TGEKPYHCLD CGKSFSHSSH LTAHQRTHRG VRPYACPLCG KSFSRRSNLH RHEKIHTTGP KALAMLMLGA AAAGALATPP PAPT
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