About Olfactory receptor 5F1
Olfactory receptor 5F1 (OR5F1) is a protein
from Homo sapiens identified by UniProt accession
O95221, 314 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | Olfactory receptor 5F1 |
|---|
| UniProt accession | O95221 |
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| Gene | OR5F1 |
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| Organism | Homo sapiens |
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| Length | 314 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (12)
Diseases linked to this target (Open Targets).
- neuroblastoma · score 0.21
- clear cell renal carcinoma · score 0.18
- hepatocellular carcinoma · score 0.18
- ovarian cancer · score 0.18
- low grade glioma · score 0.18
- multiple myeloma · score 0.16
- diffuse large B-cell lymphoma · score 0.10
- colorectal adenocarcinoma · score 0.04
- pancreatic adenocarcinoma · score 0.03
- leukocyte count · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95221-F1 | alphafold | PREDICTED | 89.22 | — |
Amino-acid sequence (314 residues)
MTRKNYTSLT EFVLLGLADT LELQIILFLF FLVIYTLTVL GNLGMILLIR IDSQLHTPMY FFLANLSFVD VCNSTTITPK MLADLLSEKK TISFAGCFLQ MYFFISLATT ECILFGLMAY DRYAAICRPL LYSLIMSRTV YLKMAAGAFA AGLLNFMVNT SHVSSLSFCD SNVIHHFFCD SPPLFKLSCS DTILKESISS ILAGVNIVGT LLVILSSYSY VLFSIFSMHS GEGRHRAFST CASHLTAIIL FYATCIYTYL RPSSSYSLNQ DKVASVFYTV VIPMLNPLIY SLRSKEVKKA LANVISRKRT SSFL
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