About Homeobox protein VENTX
Homeobox protein VENTX (VENTX) is a protein
from Homo sapiens identified by UniProt accession
O95231, 258 residues long.
MolForge cross-references it against 0 known binders and
35 disease associations.
Target properties
| Protein name | Homeobox protein VENTX |
|---|
| UniProt accession | O95231 |
|---|
| Gene | VENTX |
|---|
| Organism | Homo sapiens |
|---|
| Length | 258 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (35)
Diseases linked to this target (Open Targets).
- lung carcinoma · score 0.17
- testosterone measurement · score 0.14
- cancer · score 0.05
- acute myeloid leukemia · score 0.05
- non-small cell lung carcinoma · score 0.04
- neoplasm · score 0.04
- visual perception measurement · score 0.02
- erythroleukemia · score 0.01
- myelodysplastic syndrome · score 0.01
- holoprosencephaly · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95231-F1 | alphafold | PREDICTED | 63.24 | — |
Amino-acid sequence (258 residues)
MRLSSSPPRG PQQLSSFGSV DWLSQSSCSG PTHTPRPADF SLGSLPGPGQ TSGAREPPQA VSIKEAAGSS NLPAPERTMA GLSKEPNTLR APRVRTAFTM EQVRTLEGVF QHHQYLSPLE RKRLAREMQL SEVQIKTWFQ NRRMKHKRQM QDPQLHSPFS GSLHAPPAFY STSSGLANGL QLLCPWAPLS GPQALMLPPG SFWGLCQVAQ EALASAGASC CGQPLASHPP TPGRPSLGPA LSTGPRGLCA MPQTGDAF
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