Golgi SNAP receptor complex member 1 (GOSR1)

About Golgi SNAP receptor complex member 1

Golgi SNAP receptor complex member 1 (GOSR1) is a protein from Homo sapiens identified by UniProt accession O95249, 250 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.

Target properties

Protein name	Golgi SNAP receptor complex member 1
UniProt accession	O95249
Gene	GOSR1
Organism	Homo sapiens
Length	250 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (30)

Diseases linked to this target (Open Targets).

self reported educational attainment · score 0.23
high density lipoprotein cholesterol measurement · score 0.20
cognitive function measurement · score 0.17
Abnormality of the immune system · score 0.14
breast milk measurement · score 0.13
mathematical ability · score 0.12
breast adenocarcinoma · score 0.10
lean body mass · score 0.08
intelligence · score 0.08
insomnia measurement · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O95249-F1	alphafold	PREDICTED	84.32	—

Amino-acid sequence (250 residues)

MAAGTSSYWE DLRKQARQLE NELDLKLVSF SKLCTSYSHS STRDGRRDRY SSDTTPLLNG SSQDRMFETM AIEIEQLLAR LTGVNDKMAE YTNSAGVPSL NAALMHTLQR HRDILQDYTH EFHKTKANFM AIRERENLMG SVRKDIESYK SGSGVNNRRT ELFLKEHDHL RNSDRLIEET ISIAMATKEN MTSQRGMLKS IHSKMNTLAN RFPAVNSLIQ RINLRKRRDS LILGGVIGIC TILLLLYAFH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards