About Brain mitochondrial carrier protein 1
Brain mitochondrial carrier protein 1 (SLC25A14) is a protein
from Homo sapiens identified by UniProt accession
O95258, 325 residues long.
MolForge cross-references it against 0 known binders and
17 disease associations.
Target properties
| Protein name | Brain mitochondrial carrier protein 1 |
|---|
| UniProt accession | O95258 |
|---|
| Gene | SLC25A14 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 325 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (17)
Diseases linked to this target (Open Targets).
- diabetes mellitus · score 0.01
- Autism · score 0.01
- cancer · score 0.01
- neoplasm · score 0.00
- Obesity · score 0.00
- Stroke · score 0.00
- atherosclerosis · score 0.00
- schizophrenia · score 0.00
- nonpapillary renal cell carcinoma · score 0.00
- myeloid sarcoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95258-F1 | alphafold | PREDICTED | 78.50 | — |
Amino-acid sequence (325 residues)
MGIFPGIILI FLRVKFATAA VIVSGHQKST TVSHEMSGLN WKPFVYGGLA SIVAEFGTFP VDLTKTRLQV QGQSIDARFK EIKYRGMFHA LFRICKEEGV LALYSGIAPA LLRQASYGTI KIGIYQSLKR LFVERLEDET LLINMICGVV SGVISSTIAN PTDVLKIRMQ AQGSLFQGSM IGSFIDIYQQ EGTRGLWRGV VPTAQRAAIV VGVELPVYDI TKKHLILSGM MGDTILTHFV SSFTCGLAGA LASNPVDVVR TRMMNQRAIV GHVDLYKGTV DGILKMWKHE GFFALYKGFW PNWLRLGPWN IIFFITYEQL KRLQI
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