Cyclin-D1-binding protein 1 (CCNDBP1)

About Cyclin-D1-binding protein 1

Cyclin-D1-binding protein 1 (CCNDBP1) is a protein from Homo sapiens identified by UniProt accession O95273, 360 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.

Target properties

Protein name	Cyclin-D1-binding protein 1
UniProt accession	O95273
Gene	CCNDBP1
Organism	Homo sapiens
Length	360 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (67)

Diseases linked to this target (Open Targets).

hereditary spherocytosis · score 0.12
hematocrit · score 0.08
non-small cell lung carcinoma · score 0.07
neoplasm · score 0.07
colitis · score 0.05
dedifferentiated liposarcoma · score 0.04
glycine N-methyltransferase deficiency · score 0.04
Crigler-Najjar syndrome type 2 · score 0.04
Gilbert syndrome · score 0.04
high density lipoprotein cholesterol measurement · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O95273-F1	alphafold	PREDICTED	87.10	—

Amino-acid sequence (360 residues)

MASATAPAAA VPTLASPLEQ LRHLAEELRL LLPRVRVGEA QETTEEFNRE MFWRRLNEAA VTVSREATTL TIVFSQLPLP SPQETQKFCE QVHAAIKAFI AVYYLLPKDQ GITLRKLVRG ATLDIVDGMA QLMEVLSVTP TQSPENNDLI SYNSVWVACQ QMPQIPRDNK AAALLMLTKN VDFVKDAHEE MEQAVEECDP YSGLLNDTEE NNSDNHNHED DVLGFPSNQD LYWSEDDQEL IIPCLALVRA SKACLKKIRM LVAENGKKDQ VAQLDDIVDI SDEISPSVDD LALSIYPPMC HLTVRINSAK LVSVLKKALE ITKASHVTPQ PEDSWIPLLI NAIDHCMNRI KELTQSELEL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards