About Myelin protein zero-like protein 1
Myelin protein zero-like protein 1 (MPZL1) is a protein
from Homo sapiens identified by UniProt accession
O95297, 269 residues long.
MolForge cross-references it against 0 known binders and
36 disease associations.
Target properties
| Protein name | Myelin protein zero-like protein 1 |
|---|
| UniProt accession | O95297 |
|---|
| Gene | MPZL1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 269 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (36)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- gallbladder carcinoma · score 0.08
- neoplasm · score 0.04
- gonorrhea · score 0.03
- hepatocellular carcinoma · score 0.03
- non-small cell lung carcinoma · score 0.03
- protein measurement · score 0.03
- cancer · score 0.02
- schizophrenia · score 0.02
- hypertrophic cardiomyopathy · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95297-F1 | alphafold | PREDICTED | 76.41 | — |
Amino-acid sequence (269 residues)
MAASAGAGAV IAAPDSRRWL WSVLAAALGL LTAGVSALEV YTPKEIFVAN GTQGKLTCKF KSTSTTGGLT SVSWSFQPEG ADTTVSFFHY SQGQVYLGNY PPFKDRISWA GDLDKKDASI NIENMQFIHN GTYICDVKNP PDIVVQPGHI RLYVVEKENL PVFPVWVVVG IVTAVVLGLT LLISMILAVL YRRKNSKRDY TGCSTSESLS PVKQAPRKSP SDTEGLVKSL PSGSHQGPVI YAQLDHSGGH HSDKINKSES VVYADIRKN
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