About Peptidyl-prolyl cis-trans isomerase FKBP9
Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) is a protein
from Homo sapiens identified by UniProt accession
O95302, 570 residues long.
MolForge cross-references it against 0 known binders and
144 disease associations.
Target properties
| Protein name | Peptidyl-prolyl cis-trans isomerase FKBP9 |
|---|
| UniProt accession | O95302 |
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| Gene | FKBP9 |
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| Organism | Homo sapiens |
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| Length | 570 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (144)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.34
- head and neck squamous cell carcinoma · score 0.30
- lung adenocarcinoma · score 0.30
- gastric adenocarcinoma · score 0.30
- reticulocyte count · score 0.28
- mean corpuscular volume · score 0.28
- glioblastoma multiforme · score 0.27
- ovarian cancer · score 0.25
- endometrial cancer · score 0.25
- sex hormone-binding globulin measurement · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95302-F1 | alphafold | PREDICTED | 89.10 | — |
Amino-acid sequence (570 residues)
MAFRGWRPPP PPLLLLLLWV TGQAAPVAGL GSDAELQIER RFVPDECPRT VRSGDFVRYH YVGTFPDGQK FDSSYDRDST FNVFVGKGQL ITGMDQALVG MCVNERRFVK IPPKLAYGNE GVSGVIPPNS VLHFDVLLMD IWNSEDQVQI HTYFKPPSCP RTIQVSDFVR YHYNGTFLDG TLFDSSHNRM KTYDTYVGIG WLIPGMDKGL LGMCVGEKRI ITIPPFLAYG EDGDGKDIPG QASLVFDVAL LDLHNPKDSI SIENKVVPEN CERISQSGDF LRYHYNGTLL DGTLFDSSYS RNRTFDTYIG QGYVIPGMDE GLLGVCIGEK RRIVVPPHLG YGEEGRGNIP GSAVLVFDIH VIDFHNPSDS ISITSHYKPP DCSVLSKKGD YLKYHYNASL LDGTLLDSTW NLGKTYNIVL GSGQVVLGMD MGLREMCVGE KRTVIIPPHL GYGEAGVDGE VPGSAVLVFD IELLELVAGL PEGYMFIWNG EVSPNLFEEI DKDGNGEVLL EEFSEYIHAQ VASGKGKLAP GFDAELIVKN MFTNQDRNGD GKVTAEEFKL KDQEAKHDEL
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