About CUGBP Elav-like family member 2
CUGBP Elav-like family member 2 (CELF2) is a protein
from Homo sapiens identified by UniProt accession
O95319, 508 residues long.
MolForge cross-references it against 0 known binders and
156 disease associations.
Target properties
| Protein name | CUGBP Elav-like family member 2 |
|---|
| UniProt accession | O95319 |
|---|
| Gene | CELF2 |
|---|
| Organism | Homo sapiens |
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| Length | 508 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (156)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.42
- wellbeing measurement · score 0.38
- mathematical ability · score 0.37
- Neurodevelopmental disorder · score 0.37
- undetermined early-onset epileptic encephalopathy · score 0.37
- age at first sexual intercourse measurement · score 0.37
- neuroticism measurement · score 0.35
- protein measurement · score 0.34
- mean platelet volume · score 0.34
- attention deficit hyperactivity disorder · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95319-F1 | alphafold | PREDICTED | 64.57 | — |
Amino-acid sequence (508 residues)
MRCPKSAVTM RNEELLLSNG TANKMNGALD HSDQPDPDAI KMFVGQIPRS WSEKELKELF EPYGAVYQIN VLRDRSQNPP QSKGCCFVTF YTRKAALEAQ NALHNIKTLP GMHHPIQMKP ADSEKSNAVE DRKLFIGMVS KKCNENDIRV MFSPFGQIEE CRILRGPDGL SRGCAFVTFS TRAMAQNAIK AMHQSQTMEG CSSPIVVKFA DTQKDKEQRR LQQQLAQQMQ QLNTATWGNL TGLGGLTPQY LALLQQATSS SNLGAFSGIQ QMAGMNALQL QNLATLAAAA AAAQTSATST NANPLSTTSS ALGALTSPVA ASTPNSTAGA AMNSLTSLGT LQGLAGATVG LNNINALAGM AALNGGLGAT GLTNGTAGTM DALTQAYSGI QQYAAAALPT LYSQSLLQQQ SAAGSQKEGP EGANLFIYHL PQEFGDQDIL QMFMPFGNVI SAKVFIDKQT NLSKCFGFVS YDNPVSAQAA IQAMNGFQIG MKRLKVQLKR SKNDSKPY
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