About Olfactory receptor 2C1
Olfactory receptor 2C1 (OR2C1) is a protein
from Homo sapiens identified by UniProt accession
O95371, 312 residues long.
MolForge cross-references it against 0 known binders and
6 disease associations.
Target properties
| Protein name | Olfactory receptor 2C1 |
|---|
| UniProt accession | O95371 |
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| Gene | OR2C1 |
|---|
| Organism | Homo sapiens |
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| Length | 312 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (6)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.22
- neuroblastoma · score 0.21
- prostate adenocarcinoma · score 0.18
- IGF-1 measurement · score 0.03
- glioblastoma multiforme · score 0.01
- Vitiligo · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95371-F1 | alphafold | PREDICTED | 82.54 | — |
Amino-acid sequence (312 residues)
MDGVNDSSLQ GFVLMGISDH PQLEMIFFIA ILFSYLLTLL GNSTIILLSR LEARLHTPMY FFLSNLSSLD LAFATSSVPQ MLINLWGPGK TISYGGCITQ LYVFLWLGAT ECILLVVMAF DRYVAVCRPL RYTAIMNPQL CWLLAVIACL GGLGNSVIQS TFTLQLPLCG HRRVEGFLCE VPAMIKLACG DTSLNQAVLN GVCTFFTAVP LSIIVISYCL IAQAVLKIRS AEGRRKAFNT CLSHLLVVFL FYGSASYGYL LPAKNSKQDQ GKFISLFYSL VTPMVNPLIY TLRNMEVKGA LRRLLGKGRE VG
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