About Adenylyltransferase and sulfurtransferase MOCS3
Adenylyltransferase and sulfurtransferase MOCS3 (MOCS3) is a protein
from Homo sapiens identified by UniProt accession
O95396, 460 residues long.
MolForge cross-references it against 0 known binders and
15 disease associations.
Target properties
| Protein name | Adenylyltransferase and sulfurtransferase MOCS3 |
|---|
| UniProt accession | O95396 |
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| Gene | MOCS3 |
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| Organism | Homo sapiens |
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| Length | 460 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (15)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.20
- Non-immune hydrops fetalis · score 0.11
- body fat percentage · score 0.05
- diffuse plaque measurement · score 0.04
- self reported educational attainment · score 0.04
- bipolar disorder · score 0.04
- sex hormone-binding globulin measurement · score 0.03
- mean reticulocyte volume · score 0.02
- prostate carcinoma · score 0.02
- chronic obstructive pulmonary disease · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95396-F1 | alphafold | PREDICTED | 91.55 | — |
Amino-acid sequence (460 residues)
MASREEVLAL QAEVAQREEE LNSLKQKLAS ALLAEQEPQP ERLVPVSPLP PKAALSRDEI LRYSRQLVLP ELGVHGQLRL GTACVLIVGC GGLGCPLAQY LAAAGVGRLG LVDYDVVEMS NLARQVLHGE ALAGQAKAFS AAASLRRLNS AVECVPYTQA LTPATALDLV RRYDVVADCS DNVPTRYLVN DACVLAGRPL VSASALRFEG QITVYHYDGG PCYRCIFPQP PPAETVTNCA DGGVLGVVTG VLGCLQALEV LKIAAGLGPS YSGSLLLFDA LRGHFRSIRL RSRRLDCAAC GERPTVTDLL DYEAFCGSSA TDKCRSLQLL SPEERVSVTD YKRLLDSGAF HLLLDVRPQV EVDICRLPHA LHIPLKHLER RDAESLKLLK EAIWEEKQGT QEGAAVPIYV ICKLGNDSQK AVKILQSLSA AQELDPLTVR DVVGGLMAWA AKIDGTFPQY
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