Urotensin-2 (UTS2)

About Urotensin-2

Urotensin-2 (UTS2) is a protein from Homo sapiens identified by UniProt accession O95399, 124 residues long. MolForge cross-references it against 0 known binders and 195 disease associations.

Target properties

Protein name	Urotensin-2
UniProt accession	O95399
Gene	UTS2
Organism	Homo sapiens
Length	124 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (195)

Diseases linked to this target (Open Targets).

chronotype measurement · score 0.27
sitting height measurement · score 0.21
head and neck squamous cell carcinoma · score 0.16
testosterone measurement · score 0.11
rheumatoid arthritis · score 0.09
migraine disorder · score 0.07
Crohn's disease · score 0.07
hepatocellular carcinoma · score 0.06
vital capacity · score 0.06
neutrophil count · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O95399-F1	alphafold	PREDICTED	58.43	—

Amino-acid sequence (124 residues)

MYKLASCCLL FIGFLNPLLS LPLLDSREIS FQLSAPHEDA RLTPEELERA SLLQILPEML GAERGDILRK ADSSTNIFNP RGNLRKFQDF SGQDPNILLS HLLARIWKPY KKRETPDCFW KYCV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards