Protein cornichon homolog 1 (CNIH1)

About Protein cornichon homolog 1

Protein cornichon homolog 1 (CNIH1) is a protein from Homo sapiens identified by UniProt accession O95406, 144 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.

Target properties

Protein name	Protein cornichon homolog 1
UniProt accession	O95406
Gene	CNIH1
Organism	Homo sapiens
Length	144 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (31)

Diseases linked to this target (Open Targets).

reticulocyte count · score 0.21
reticulocyte measurement · score 0.20
Immature Reticulocyte Fraction Measurement · score 0.17
refractive error · score 0.16
Myopia · score 0.14
cortical surface area measurement · score 0.14
brain volume measurement · score 0.13
refractive error measurement · score 0.13
lung adenocarcinoma · score 0.13
appendicular lean mass · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O95406-F1	alphafold	PREDICTED	84.34	—

Amino-acid sequence (144 residues)

MAFTFAAFCY MLALLLTAAL IFFAIWHIIA FDELKTDYKN PIDQCNTLNP LVLPEYLIHA FFCVMFLCAA EWLTLGLNMP LLAYHIWRYM SRPVMSGPGL YDPTTIMNAD ILAYCQKEGW CKLAFYLLAF FYYLYGMIYV LVSS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards