Membrane protein BRI3 (BRI3)

About Membrane protein BRI3

Membrane protein BRI3 (BRI3) is a protein from Homo sapiens identified by UniProt accession O95415, 125 residues long. MolForge cross-references it against 0 known binders and 96 disease associations.

Target properties

Protein name	Membrane protein BRI3
UniProt accession	O95415
Gene	BRI3
Organism	Homo sapiens
Length	125 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (96)

Diseases linked to this target (Open Targets).

sex hormone-binding globulin measurement · score 0.42
bilirubin measurement · score 0.30
heel bone mineral density · score 0.30
testosterone measurement · score 0.29
low density lipoprotein cholesterol measurement · score 0.27
monocyte count · score 0.25
lymphocyte count · score 0.25
apolipoprotein B measurement · score 0.23
total cholesterol measurement · score 0.22
erythrocyte count · score 0.22

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O95415-F1	alphafold	PREDICTED	65.12	—

Amino-acid sequence (125 residues)

MDHKPLLQER PPAYNLEAGQ GDYACGPHGY GAIPAAPPPP PYPYLVTGIP THHPRVYNIH SRTVTRYPAN SIVVVGGCPV CRVGVLEDCF TFLGIFLAII LFPFGFICCF ALRKRRCPNC GATFA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards