Dexamethasone-induced protein (DEXI)

About Dexamethasone-induced protein

Dexamethasone-induced protein (DEXI) is a protein from Homo sapiens identified by UniProt accession O95424, 95 residues long. MolForge cross-references it against 0 known binders and 60 disease associations.

Target properties

Protein name	Dexamethasone-induced protein
UniProt accession	O95424
Gene	DEXI
Organism	Homo sapiens
Length	95 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (60)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.33
blood protein measurement · score 0.15
lymphocyte count · score 0.14
sex hormone-binding globulin measurement · score 0.13
cystatin C measurement · score 0.10
serum albumin measurement · score 0.10
eosinophil count · score 0.10
gut microbiome measurement · score 0.09
asthma · score 0.09
waist-hip ratio · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O95424-F1	alphafold	PREDICTED	68.94	—

Amino-acid sequence (95 residues)

MLGARVAAHL DALGPLVPYV PPPLLPSMFY VGLFFVNVLI LYYAFLMEYI VLNVGLVFLP EDMDQALVDL GVLSDPGSGL YDADSELDVF DAYLE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards