About Sodium-dependent phosphate transport protein 2B
Sodium-dependent phosphate transport protein 2B (SLC34A2) is a protein
from Homo sapiens identified by UniProt accession
O95436, 690 residues long.
MolForge cross-references it against 0 known binders and
241 disease associations.
Target properties
| Protein name | Sodium-dependent phosphate transport protein 2B |
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| UniProt accession | O95436 |
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| Gene | SLC34A2 |
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| Organism | Homo sapiens |
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| Length | 690 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (241)
Diseases linked to this target (Open Targets).
- pulmonary alveolar microlithiasis · score 0.71
- lung adenocarcinoma · score 0.40
- non-small cell lung carcinoma · score 0.40
- squamous cell lung carcinoma · score 0.37
- acute myeloid leukemia · score 0.33
- cutaneous melanoma · score 0.33
- colorectal adenocarcinoma · score 0.31
- melanoma · score 0.31
- hepatocellular carcinoma · score 0.30
- lung carcinoma · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95436-F1 | alphafold | PREDICTED | 72.93 | — |
Amino-acid sequence (690 residues)
MAPWPELGDA QPNPDKYLEG AAGQQPTAPD KSKETNKTDN TEAPVTKIEL LPSYSTATLI DEPTEVDDPW NLPTLQDSGI KWSERDTKGK ILCFFQGIGR LILLLGFLYF FVCSLDILSS AFQLVGGKMA GQFFSNSSIM SNPLLGLVIG VLVTVLVQSS STSTSIVVSM VSSSLLTVRA AIPIIMGANI GTSITNTIVA LMQVGDRSEF RRAFAGATVH DFFNWLSVLV LLPVEVATHY LEIITQLIVE SFHFKNGEDA PDLLKVITKP FTKLIVQLDK KVISQIAMND EKAKNKSLVK IWCKTFTNKT QINVTVPSTA NCTSPSLCWT DGIQNWTMKN VTYKENIAKC QHIFVNFHLP DLAVGTILLI LSLLVLCGCL IMIVKILGSV LKGQVATVIK KTINTDFPFP FAWLTGYLAI LVGAGMTFIV QSSSVFTSAL TPLIGIGVIT IERAYPLTLG SNIGTTTTAI LAALASPGNA LRSSLQIALC HFFFNISGIL LWYPIPFTRL PIRMAKGLGN ISAKYRWFAV FYLIIFFFLI PLTVFGLSLA GWRVLVGVGV PVVFIIILVL CLRLLQSRCP RVLPKKLQNW NFLPLWMRSL KPWDAVVSKF TGCFQMRCCC CCRVCCRACC LLCDCPKCCR CSKCCEDLEE AQEGQDVPVK APETFDNITI SREAQGEVPA SDSKTECTAL
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