About Apolipoprotein M
Apolipoprotein M (APOM) is a protein
from Homo sapiens identified by UniProt accession
O95445, 188 residues long.
MolForge cross-references it against 0 known binders and
201 disease associations.
Target properties
| Protein name | Apolipoprotein M |
|---|
| UniProt accession | O95445 |
|---|
| Gene | APOM |
|---|
| Organism | Homo sapiens |
|---|
| Length | 188 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (201)
Diseases linked to this target (Open Targets).
- cutaneous melanoma · score 0.18
- breast adenocarcinoma · score 0.15
- type 2 diabetes mellitus · score 0.10
- Sepsis · score 0.10
- complement C4 measurement · score 0.10
- Systemic lupus erythematosus · score 0.08
- chronic obstructive pulmonary disease · score 0.08
- insulin resistance · score 0.08
- Hyperlipidemia · score 0.08
- diabetes mellitus · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95445-F1 | alphafold | PREDICTED | 89.47 | — |
Amino-acid sequence (188 residues)
MFHQIWAALL YFYGIILNSI YQCPEHSQLT TLGVDGKEFP EVHLGQWYFI AGAAPTKEEL ATFDPVDNIV FNMAAGSAPM QLHLRATIRM KDGLCVPRKW IYHLTEGSTD LRTEGRPDMK TELFSSSCPG GIMLNETGQG YQRFLLYNRS PHPPEKCVEE FKSLTSCLDS KAFLLTPRNQ EACELSNN
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