About Lebercilin-like protein
Lebercilin-like protein (LCA5L) is a protein
from Homo sapiens identified by UniProt accession
O95447, 670 residues long.
MolForge cross-references it against 0 known binders and
83 disease associations.
Target properties
| Protein name | Lebercilin-like protein |
|---|
| UniProt accession | O95447 |
|---|
| Gene | LCA5L |
|---|
| Organism | Homo sapiens |
|---|
| Length | 670 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (83)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.27
- sitting height measurement · score 0.18
- body height · score 0.14
- pulse pressure measurement · score 0.13
- inflammatory bowel disease · score 0.10
- platelet crit · score 0.10
- platelet count · score 0.07
- mean platelet volume · score 0.06
- dehydrated hereditary stomatocytosis · score 0.05
- Rh deficiency syndrome · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95447-F1 | alphafold | PREDICTED | 62.30 | — |
Amino-acid sequence (670 residues)
MSLADLTKTN IDEHFFGVAL ENNRRSAACK RSPGTGDFSR NSNASNKSVD YSRSQCSCGS LSSQYDYSED FLCDCSEKAI NRNYLKQPVV KEKEKKKYNV SKISQSKGQK EISVEKKHTW NASLFNSQIH MIAQRRDAMA HRILSARLHK IKGLKNELAD MHHKLEAILT ENQFLKQLQL RHLKAIGKYE NSQNNLPQIM AKHQNEVKNL RQLLRKSQEK ERTLSRKLRE TDSQLLKTKD ILQALQKLSE DKNLAEREEL THKLSIITTK MDANDKKIQS LEKQLRLNCR AFSRQLAIET RKTLAAQTAT KTLQVEVKHL QQKLKEKDRE LEIKNIYSHR ILKNLHDTED YPKVSSTKSV QADRKILPFT SMRHQGTQKS DVPPLTTKGK KATGNIDHKE KSTEINHEIP HCVNKLPKQE DSKRKYEDLS GEEKHLEVQI LLENTGRQKD KKEDQEKKNI FVKEEQELPP KIIEVIHPER ESNQEDVLVR EKFKRSMQRN GVDDTLGKGT APYTKGPLRQ RRHYSFTEAT ENLHHGLPAS GGPANAGNMR YSHSTGKHLS NREEMELEHS DSGYEPSFGK SSRIKVKDTT FRDKKSSLME ELFGSGYVLK TDQSSPGVAK GSEEPLQSKE SHPLPPSQAS TSHAFGDSKV TVVNSIKPSS PTEGKRKIII
Explore Lebercilin-like protein with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets