About Neuroendocrine secretory protein 55
Neuroendocrine secretory protein 55 (GNAS) is a protein
from Homo sapiens identified by UniProt accession
O95467, 245 residues long.
MolForge cross-references it against 0 known binders and
813 disease associations.
Target properties
| Protein name | Neuroendocrine secretory protein 55 |
|---|
| UniProt accession | O95467 |
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| Gene | GNAS |
|---|
| Organism | Homo sapiens |
|---|
| Length | 245 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (813)
Diseases linked to this target (Open Targets).
- pseudohypoparathyroidism type 1A · score 0.85
- pseudohypoparathyroidism type 1C · score 0.82
- McCune-Albright syndrome · score 0.82
- pseudohypoparathyroidism type 1B · score 0.81
- ACTH-independent macronodular adrenal hyperplasia 1 · score 0.81
- Albright hereditary osteodystrophy · score 0.79
- pseudopseudohypoparathyroidism · score 0.78
- progressive osseous heteroplasia · score 0.76
- Pituitary Gland Adenoma · score 0.64
- pancreatic adenocarcinoma · score 0.60
Amino-acid sequence (245 residues)
MDRRSRAQQW RRARHNYNDL CPPIGRRAAT ALLWLSCSIA LLRALATSNA RAQQRAAAQQ RRSFLNAHHR SGAQVFPESP ESESDHEHEE ADLELSLPEC LEYEEEFDYE TESETESEIE SETDFETEPE TAPTTEPETE PEDDRGPVVP KHSTFGQSLT QRLHALKLRS PDASPSRAPP STQEPQSPRE GEELKPEDKD PRDPEESKEP KEEKQRRRCK PKKPTRRDAS PESPSKKGPI PIRRH
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