About Claudin-7
Claudin-7 (CLDN7) is a protein
from Homo sapiens identified by UniProt accession
O95471, 211 residues long.
MolForge cross-references it against 0 known binders and
529 disease associations.
Target properties
| Protein name | Claudin-7 |
|---|
| UniProt accession | O95471 |
|---|
| Gene | CLDN7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 211 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (529)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.25
- diastolic blood pressure · score 0.23
- birth weight · score 0.23
- pulse pressure measurement · score 0.21
- waist-hip ratio · score 0.21
- platelet count · score 0.17
- Diuretic use measurement · score 0.16
- eosinophil count · score 0.16
- head and neck squamous cell carcinoma · score 0.15
- lymphocyte percentage of leukocytes · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95471-F1 | alphafold | PREDICTED | 82.64 | — |
Amino-acid sequence (211 residues)
MANSGLQLLG FSMALLGWVG LVACTAIPQW QMSSYAGDNI ITAQAMYKGL WMDCVTQSTG MMSCKMYDSV LALSAALQAT RALMVVSLVL GFLAMFVATM GMKCTRCGGD DKVKKARIAM GGGIIFIVAG LAALVACSWY GHQIVTDFYN PLIPTNIKYE FGPAIFIGWA GSALVILGGA LLSCSCPGNE SKAGYRVPRS YPKSNSSKEY V
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