About CTD nuclear envelope phosphatase 1
CTD nuclear envelope phosphatase 1 (CTDNEP1) is a protein
from Homo sapiens identified by UniProt accession
O95476, 244 residues long.
MolForge cross-references it against 0 known binders and
55 disease associations.
Target properties
| Protein name | CTD nuclear envelope phosphatase 1 |
|---|
| UniProt accession | O95476 |
|---|
| Gene | CTDNEP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 244 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (55)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.21
- vital capacity · score 0.21
- birth weight · score 0.20
- neutrophil percentage of leukocytes · score 0.13
- platelet count · score 0.13
- alkaline phosphatase measurement · score 0.12
- systolic blood pressure · score 0.12
- body height at birth · score 0.11
- lymphocyte percentage of leukocytes · score 0.10
- hypertension · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95476-F1 | alphafold | PREDICTED | 90.52 | — |
Amino-acid sequence (244 residues)
MMRTQCLLGL RTFVAFAAKL WSFFIYLLRR QIRTVIQYQT VRYDILPLSP VSRNRLAQVK RKILVLDLDE TLIHSHHDGV LRPTVRPGTP PDFILKVVID KHPVRFFVHK RPHVDFFLEV VSQWYELVVF TASMEIYGSA VADKLDNSRS ILKRRYYRQH CTLELGSYIK DLSVVHSDLS SIVILDNSPG AYRSHPDNAI PIKSWFSDPS DTALLNLLPM LDALRFTADV RSVLSRNLHQ HRLW
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