About Claudin-9
Claudin-9 (CLDN9) is a protein
from Homo sapiens identified by UniProt accession
O95484, 217 residues long.
MolForge cross-references it against 0 known binders and
55 disease associations.
Target properties
| Protein name | Claudin-9 |
|---|
| UniProt accession | O95484 |
|---|
| Gene | CLDN9 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 217 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (55)
Diseases linked to this target (Open Targets).
- hearing loss, autosomal recessive 116 · score 0.62
- hearing loss · score 0.27
- endometrial cancer · score 0.23
- glioblastoma multiforme · score 0.16
- head and neck squamous cell carcinoma · score 0.15
- Hearing impairment · score 0.12
- Pendred syndrome · score 0.12
- nonsyndromic genetic hearing loss · score 0.12
- autosomal dominant nonsyndromic hearing loss · score 0.12
- gastric adenocarcinoma · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95484-F1 | alphafold | PREDICTED | 81.16 | — |
Amino-acid sequence (217 residues)
MASTGLELLG MTLAVLGWLG TLVSCALPLW KVTAFIGNSI VVAQVVWEGL WMSCVVQSTG QMQCKVYDSL LALPQDLQAA RALCVIALLL ALLGLLVAIT GAQCTTCVED EGAKARIVLT AGVILLLAGI LVLIPVCWTA HAIIQDFYNP LVAEALKREL GASLYLGWAA AALLMLGGGL LCCTCPPPQV ERPRGPRLGY SIPSRSGASG LDKRDYV
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