About Pantetheinase
Pantetheinase (VNN1) is a protein
from Homo sapiens identified by UniProt accession
O95497, 513 residues long.
MolForge cross-references it against 0 known binders and
154 disease associations.
Target properties
| Protein name | Pantetheinase |
|---|
| UniProt accession | O95497 |
|---|
| Gene | VNN1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 513 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (154)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.10
- colitis · score 0.07
- Barrett's esophagus · score 0.07
- type 2 diabetes mellitus · score 0.06
- hypertension · score 0.06
- ulcerative colitis · score 0.06
- isolated asymptomatic elevation of creatine phosphokinase · score 0.06
- fetal growth restriction · score 0.06
- esophageal adenocarcinoma · score 0.05
- Sepsis · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95497-F1 | alphafold | PREDICTED | 92.35 | — |
Amino-acid sequence (513 residues)
MTTQLPAYVA ILLFYVSRAS CQDTFTAAVY EHAAILPNAT LTPVSREEAL ALMNRNLDIL EGAITSAADQ GAHIIVTPED AIYGWNFNRD SLYPYLEDIP DPEVNWIPCN NRNRFGQTPV QERLSCLAKN NSIYVVANIG DKKPCDTSDP QCPPDGRYQY NTDVVFDSQG KLVARYHKQN LFMGENQFNV PKEPEIVTFN TTFGSFGIFT CFDILFHDPA VTLVKDFHVD TIVFPTAWMN VLPHLSAVEF HSAWAMGMRV NFLASNIHYP SKKMTGSGIY APNSSRAFHY DMKTEEGKLL LSQLDSHPSH SAVVNWTSYA SSIEALSSGN KEFKGTVFFD EFTFVKLTGV AGNYTVCQKD LCCHLSYKMS ENIPNEVYAL GAFDGLHTVE GRYYLQICTL LKCKTTNLNT CGDSAETAST RFEMFSLSGT FGTQYVFPEV LLSENQLAPG EFQVSTDGRL FSLKPTSGPV LTVTLFGRLY EKDWASNASS GLTAQARIIM LIVIAPIVCS LSW
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