About Neuronal pentraxin receptor
Neuronal pentraxin receptor (NPTXR) is a protein
from Homo sapiens identified by UniProt accession
O95502, 500 residues long.
MolForge cross-references it against 0 known binders and
110 disease associations.
Target properties
| Protein name | Neuronal pentraxin receptor |
|---|
| UniProt accession | O95502 |
|---|
| Gene | NPTXR |
|---|
| Organism | Homo sapiens |
|---|
| Length | 500 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (110)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.32
- age at menarche · score 0.22
- gonorrhea · score 0.07
- neoplasm · score 0.07
- mathematical ability · score 0.06
- body height · score 0.05
- esophageal squamous cell carcinoma · score 0.04
- sex hormone-binding globulin measurement · score 0.03
- hepatocellular carcinoma · score 0.03
- cancer · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95502-F1 | alphafold | PREDICTED | 75.97 | — |
Amino-acid sequence (500 residues)
MKFLAVLLAA GMLAFLGAVI CIIASVPLAA SPARALPGGA DNASVASGAA ASPGPQRSLS ALHGAGGSAG PPALPGAPAA SAHPLPPGPL FSRFLCTPLA AACPSGAQQG DAAGAAPGER EELLLLQSTA EQLRQTALQQ EARIRADQDT IRELTGKLGR CESGLPRGLQ GAGPRRDTMA DGPWDSPALI LELEDAVRAL RDRIDRLEQE LPARVNLSAA PAPVSAVPTG LHSKMDQLEG QLLAQVLALE KERVALSHSS RRQRQEVEKE LDVLQGRVAE LEHGSSAYSP PDAFKISIPI RNNYMYARVR KALPELYAFT ACMWLRSRSS GTGQGTPFSY SVPGQANEIV LLEAGHEPME LLINDKVAQL PLSLKDNGWH HICIAWTTRD GLWSAYQDGE LQGSGENLAA WHPIKPHGIL ILGQEQDTLG GRFDATQAFV GDIAQFNLWD HALTPAQVLG IANCTAPLLG NVLPWEDKLV EAFGGATKAA FDVCKGRAKA
Explore Neuronal pentraxin receptor with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets