About Uncharacterized protein C1orf105
Uncharacterized protein C1orf105 (C1orf105) is a protein
from Homo sapiens identified by UniProt accession
O95561, 183 residues long.
MolForge cross-references it against 0 known binders and
69 disease associations.
Target properties
| Protein name | Uncharacterized protein C1orf105 |
|---|
| UniProt accession | O95561 |
|---|
| Gene | C1orf105 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 183 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (69)
Diseases linked to this target (Open Targets).
- glycosylphosphatidylinositol biosynthesis defect 16 · score 0.51
- Red cell distribution width · score 0.40
- reticulocyte count · score 0.36
- mean corpuscular hemoglobin concentration · score 0.34
- Global developmental delay · score 0.34
- reticulocyte measurement · score 0.33
- hemoglobin measurement · score 0.33
- Immature Reticulocyte Fraction Measurement · score 0.31
- mean reticulocyte volume · score 0.31
- blood protein measurement · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95561-F1 | alphafold | PREDICTED | 57.66 | — |
Amino-acid sequence (183 residues)
MEKRELKASV PKFDKIPWLS EASLVNKPLV LSLPRRYPHT SATFLTSSKK NMNLPILFQV PDVLSKARRN QCDSMLLRNQ QLCSTCQEMK MVQPRTMKIP DDPKASFENC MSYRMSLHQP KFQTTPEPFH DDIPTESIHY RLPILGPRTA VFHGLLTEAY KTLKERQRSS LPRKEPIGKT TRQ
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