Vesicle transport protein SFT2B (SFT2D2)

About Vesicle transport protein SFT2B

Vesicle transport protein SFT2B (SFT2D2) is a protein from Homo sapiens identified by UniProt accession O95562, 160 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.

Target properties

Protein name	Vesicle transport protein SFT2B
UniProt accession	O95562
Gene	SFT2D2
Organism	Homo sapiens
Length	160 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (22)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.39
Alzheimer disease · score 0.29
Parkinson disease · score 0.29
multiple sclerosis · score 0.29
lysosomal storage disease · score 0.29
IGF-1 measurement · score 0.25
testosterone measurement · score 0.22
neutrophil count · score 0.07
leukocyte count · score 0.05
protein measurement · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O95562-F1	alphafold	PREDICTED	78.52	—

Amino-acid sequence (160 residues)

MDKLKKVLSG QDTEDRSGLS EVVEASSLSW STRIKGFIAC FAIGILCSLL GTVLLWVPRK GLHLFAVFYT FGNIASIGST IFLMGPVKQL KRMFEPTRLI ATIMVLLCFA LTLCSAFWWH NKGLALIFCI LQSLALTWYS LSFIPFARDA VKKCFAVCLA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards