Uncharacterized protein C22orf31 (C22orf31)

About Uncharacterized protein C22orf31

Uncharacterized protein C22orf31 (C22orf31) is a protein from Homo sapiens identified by UniProt accession O95567, 290 residues long. MolForge cross-references it against 0 known binders and 75 disease associations.

Target properties

Protein name	Uncharacterized protein C22orf31
UniProt accession	O95567
Gene	C22orf31
Organism	Homo sapiens
Length	290 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (75)

Diseases linked to this target (Open Targets).

BMI-adjusted waist-hip ratio · score 0.38
high density lipoprotein cholesterol measurement · score 0.29
physical activity measurement · score 0.25
waist-hip ratio · score 0.25
BMI-adjusted waist circumference · score 0.24
systolic blood pressure · score 0.24
cardiovascular disease · score 0.23
breast carcinoma · score 0.21
apolipoprotein A 1 measurement · score 0.21
refractive error measurement · score 0.19

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O95567-F1	alphafold	PREDICTED	56.87	—

Amino-acid sequence (290 residues)

MHPINVRRDP SIPIYGLRQS ILLNTRLQDC YVDSPALTNI WMARTCAKQN INAPAPATTS SWEVVRNPLI ASSFSLVKLV LRRQLKNKCC PPPCKFGEGK LSKRLKHKDD SVMKATQQAR KRNFISSKSK QPAGHRRPAG GIRESKESSK EKKLTVRQDL EDRYAEHVAA TQALPQDSGT AAWKGRVLLP ETQKRQQLSE DTLTIHGLPT EGYQALYHAV VEPMLWNPSG TPKRYSLELG KAIKQKLWEA LCSQGAISEG AQRDRFPGRK QPGVHEEPVL KKWPKLKSKK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards