About Follistatin-related protein 3
Follistatin-related protein 3 (FSTL3) is a protein
from Homo sapiens identified by UniProt accession
O95633, 263 residues long.
MolForge cross-references it against 0 known binders and
195 disease associations.
Target properties
| Protein name | Follistatin-related protein 3 |
|---|
| UniProt accession | O95633 |
|---|
| Gene | FSTL3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 263 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (195)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- sex hormone-binding globulin measurement · score 0.30
- lung adenocarcinoma · score 0.30
- hepatocellular carcinoma · score 0.29
- gastric adenocarcinoma · score 0.28
- squamous cell lung carcinoma · score 0.28
- head and neck squamous cell carcinoma · score 0.28
- colorectal adenocarcinoma · score 0.28
- gastric carcinoma · score 0.28
- cutaneous melanoma · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95633-F1 | alphafold | PREDICTED | 85.92 | — |
Amino-acid sequence (263 residues)
MRPGAPGPLW PLPWGALAWA VGFVSSMGSG NPAPGGVCWL QQGQEATCSL VLQTDVTRAE CCASGNIDTA WSNLTHPGNK INLLGFLGLV HCLPCKDSCD GVECGPGKAC RMLGGRPRCE CAPDCSGLPA RLQVCGSDGA TYRDECELRA ARCRGHPDLS VMYRGRCRKS CEHVVCPRPQ SCVVDQTGSA HCVVCRAAPC PVPSSPGQEL CGNNNVTYIS SCHMRQATCF LGRSIGVRHA GSCAGTPEEP PGGESAEEEE NFV
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