V-type proton ATPase subunit G 2 (ATP6V1G2)

About V-type proton ATPase subunit G 2

V-type proton ATPase subunit G 2 (ATP6V1G2) is a protein from Homo sapiens identified by UniProt accession O95670, 118 residues long. MolForge cross-references it against 0 known binders and 76 disease associations.

Target properties

Protein name	V-type proton ATPase subunit G 2
UniProt accession	O95670
Gene	ATP6V1G2
Organism	Homo sapiens
Length	118 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (76)

Diseases linked to this target (Open Targets).

breast adenocarcinoma · score 0.21
rheumatoid arthritis · score 0.18
Sepsis · score 0.12
mortality · score 0.12
myositis · score 0.10
attention deficit hyperactivity disorder · score 0.09
MHC class I polypeptide-related sequence B measurement · score 0.08
schizophrenia 15 · score 0.07
attention deficit-hyperactivity disorder 8 · score 0.07
late-onset myasthenia gravis · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O95670-F1	alphafold	PREDICTED	93.63	—

Amino-acid sequence (118 residues)

MASQSQGIQQ LLQAEKRAAE KVADARKRKA RRLKQAKEEA QMEVEQYRRE REHEFQSKQQ AAMGSQGNLS AEVEQATRRQ VQGMQSSQQR NRERVLAQLL GMVCDVRPQV HPNYRISA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards