About Phosphatidate cytidylyltransferase 2
Phosphatidate cytidylyltransferase 2 (CDS2) is a protein
from Homo sapiens identified by UniProt accession
O95674, 445 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | Phosphatidate cytidylyltransferase 2 |
|---|
| UniProt accession | O95674 |
|---|
| Gene | CDS2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 445 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (42)
Diseases linked to this target (Open Targets).
- body height · score 0.20
- breast adenocarcinoma · score 0.18
- ovarian carcinoma · score 0.17
- neurofibrillary tangles measurement · score 0.14
- visual perception measurement · score 0.05
- neutropenia, severe congenital, 2, autosomal dominant · score 0.04
- combined immunodeficiency with skin granulomas · score 0.04
- common variable immunodeficiency · score 0.03
- mean platelet volume · score 0.03
- X-Linked Combined Immunodeficiency Diseases · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95674-F1 | alphafold | PREDICTED | 81.10 | — |
Amino-acid sequence (445 residues)
MTELRQRVAH EPVAPPEDKE SESEAKVDGE TASDSESRAE SAPLPVSADD TPEVLNRALS NLSSRWKNWW VRGILTLAMI AFFFIIIYLG PMVLMIIVMC VQIKCFHEII TIGYNVYHSY DLPWFRTLSW YFLLCVNYFF YGETVTDYFF TLVQREEPLR ILSKYHRFIS FTLYLIGFCM FVLSLVKKHY RLQFYMFGWT HVTLLIVVTQ SHLVIHNLFE GMIWFIVPIS CVICNDIMAY MFGFFFGRTP LIKLSPKKTW EGFIGGFFAT VVFGLLLSYV MSGYRCFVCP VEYNNDTNSF TVDCEPSDLF RLQEYNIPGV IQSVIGWKTV RMYPFQIHSI ALSTFASLIG PFGGFFASGF KRAFKIKDFA NTIPGHGGIM DRFDCQYLMA TFVNVYIASF IRGPNPSKLI QQFLTLRPDQ QLHIFNTLRS HLIDKGMLTS TTEDE
Explore Phosphatidate cytidylyltransferase 2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets