About Ribonuclease P protein subunit p29
Ribonuclease P protein subunit p29 (POP4) is a protein
from Homo sapiens identified by UniProt accession
O95707, 220 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Ribonuclease P protein subunit p29 |
|---|
| UniProt accession | O95707 |
|---|
| Gene | POP4 |
|---|
| Organism | Homo sapiens |
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| Length | 220 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- systolic blood pressure · score 0.30
- heart rate response to exercise · score 0.29
- heart rate response to recovery post exercise · score 0.27
- diet measurement · score 0.25
- protein measurement · score 0.13
- metabolite measurement · score 0.11
- insulin resistance · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95707-F1 | alphafold | PREDICTED | 83.87 | — |
Amino-acid sequence (220 residues)
MKSVIYHALS QKEANDSDVQ PSGAQRAEAF VRAFLKRSTP RMSPQAREDQ LQRKAVVLEY FTRHKRKEKK KKAKGLSARQ RRELRLFDIK PEQQRYSLFL PLHELWKQYI RDLCSGLKPD TQPQMIQAKL LKADLHGAII SVTKSKCPSY VGITGILLQE TKHIFKIITK EDRLKVIPKL NCVFTVETDG FISYIYGSKF QLRSSERSAK KFKAKGTIDL
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