C-X-C motif chemokine 14 (CXCL14)

About C-X-C motif chemokine 14

C-X-C motif chemokine 14 (CXCL14) is a protein from Homo sapiens identified by UniProt accession O95715, 111 residues long. MolForge cross-references it against 0 known binders and 302 disease associations.

Target properties

Protein name	C-X-C motif chemokine 14
UniProt accession	O95715
Gene	CXCL14
Organism	Homo sapiens
Length	111 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (302)

Diseases linked to this target (Open Targets).

neoplasm · score 0.12
glioblastoma · score 0.09
hepatocellular carcinoma · score 0.09
head and neck squamous cell carcinoma · score 0.09
colorectal carcinoma · score 0.08
lip and oral cavity carcinoma · score 0.08
cancer · score 0.08
lung cancer · score 0.08
pachyonychia congenita · score 0.08
renal cell carcinoma · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O95715-F1	alphafold	PREDICTED	85.20	—

Amino-acid sequence (111 residues)

MSLLPRRAPP VSMRLLAAAL LLLLLALYTA RVDGSKCKCS RKGPKIRYSD VKKLEMKPKY PHCEEKMVII TTKSVSRYRG QEHCLHPKLQ STKRFIKWYN AWNEKRRVYE E

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards