About Ras-related protein Rab-3D
Ras-related protein Rab-3D (RAB3D) is a protein
from Homo sapiens identified by UniProt accession
O95716, 219 residues long.
MolForge cross-references it against 0 known binders and
47 disease associations.
Target properties
| Protein name | Ras-related protein Rab-3D |
|---|
| UniProt accession | O95716 |
|---|
| Gene | RAB3D |
|---|
| Organism | Homo sapiens |
|---|
| Length | 219 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (47)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.09
- cancer · score 0.08
- non-small cell lung carcinoma · score 0.07
- systolic blood pressure · score 0.06
- osteosarcoma · score 0.05
- esophageal squamous cell carcinoma · score 0.03
- melanoma · score 0.02
- renal cell carcinoma · score 0.02
- triglyceride measurement · score 0.02
- acute myeloid leukemia · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95716-F1 | alphafold | PREDICTED | 83.63 | — |
Amino-acid sequence (219 residues)
MASAGDTQAG PRDAADQNFD YMFKLLLIGN SSVGKTSFLF RYADDSFTPA FVSTVGIDFK VKTVYRHDKR IKLQIWDTAG QERYRTITTA YYRGAMGFLL MYDIANQESF AAVQDWATQI KTYSWDNAQV ILVGNKCDLE DERVVPAEDG RRLADDLGFE FFEASAKENI NVKQVFERLV DVICEKMNES LEPSSSSGSN GKGPAVGDAP APQPSSCSC
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