About Copine-6
Copine-6 (CPNE6) is a protein
from Homo sapiens identified by UniProt accession
O95741, 557 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | Copine-6 |
|---|
| UniProt accession | O95741 |
|---|
| Gene | CPNE6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 557 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (23)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.26
- breast adenocarcinoma · score 0.18
- glioblastoma multiforme · score 0.04
- breast carcinoma · score 0.03
- self reported educational attainment · score 0.03
- cognitive function measurement · score 0.02
- Crohn's disease · score 0.02
- psoriasis · score 0.02
- non-alcoholic fatty liver disease · score 0.01
- prostate carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95741-F1 | alphafold | PREDICTED | 86.41 | — |
Amino-acid sequence (557 residues)
MSDPEMGWVP EPPTMTLGAS RVELRVSCHG LLDRDTLTKP HPCVLLKLYS DEQWVEVERT EVLRSCSSPV FSRVLALEYF FEEKQPLQFH VFDAEDGATS PRNDTFLGST ECTLGQIVSQ TKVTKPLLLK NGKTAGKSTI TIVAEEVSGT NDYVQLTFRA YKLDNKDLFS KSDPFMEIYK TNEDQSDQLV WRTEVVKNNL NPSWEPFRLS LHSLCSCDVH RPLKFLVYDY DSSGKHDFIG EFTSTFQEMQ EGTANPGQEM QWDCINPKYR DKKKNYKSSG TVVLAQCTVE KVHTFLDYIM GGCQISFTVA IDFTASNGDP RSSQSLHCLS PRQPNHYLQA LRAVGGICQD YDSDKRFPAF GFGARIPPNF EVSHDFAINF DPENPECEEI SGVIASYRRC LPQIQLYGPT NVAPIINRVA EPAQREQSTG QATKYSVLLV LTDGVVSDMA ETRTAIVRAS RLPMSIIIVG VGNADFSDMR LLDGDDGPLR CPRGVPAARD IVQFVPFRDF KDAAPSALAK CVLAEVPRQV VEYYASQGIS PGAPRPCTLA TTPSPSP
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