About Ras-related protein Rab-36
Ras-related protein Rab-36 (RAB36) is a protein
from Homo sapiens identified by UniProt accession
O95755, 267 residues long.
MolForge cross-references it against 0 known binders and
39 disease associations.
Target properties
| Protein name | Ras-related protein Rab-36 |
|---|
| UniProt accession | O95755 |
|---|
| Gene | RAB36 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 267 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (39)
Diseases linked to this target (Open Targets).
- neuroimaging measurement · score 0.24
- brain volume measurement · score 0.24
- cortical surface area measurement · score 0.18
- neurodegenerative disease · score 0.17
- neurofibrillary tangles measurement · score 0.15
- lymphocyte count · score 0.09
- mean platelet volume · score 0.07
- bone density · score 0.07
- heel bone mineral density · score 0.07
- immunoproliferative disorder · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95755-F1 | alphafold | PREDICTED | 85.67 | — |
Amino-acid sequence (267 residues)
MRSSLTPLGP PVSRDRVIAS FPKWYTPEAC LQLREHFHGQ VSAACQRRNT GTVGLKLSKV VVVGDLYVGK TSLIHRFCKN VFDRDYKATI GVDFEIERFE IAGIPYSLQI WDTAGQEKFK CIASAYYRGA QVIITAFDLT DVQTLEHTRQ WLEDALRENE AGSCFIFLVG TKKDLLSGAA CEQAEADAVH LAREMQAEYW SVSAKTGENV KAFFSRVAAL AFEQSVLQDL ERQSSARLQV GNGDLIQMEG SPPETQESKR PSSLGCC
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