About Zinc finger protein 682
Zinc finger protein 682 (ZNF682) is a protein
from Homo sapiens identified by UniProt accession
O95780, 498 residues long.
MolForge cross-references it against 0 known binders and
33 disease associations.
Target properties
| Protein name | Zinc finger protein 682 |
|---|
| UniProt accession | O95780 |
|---|
| Gene | ZNF682 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 498 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (33)
Diseases linked to this target (Open Targets).
- X-linked severe congenital neutropenia · score 0.04
- Blackfan-Diamond anemia · score 0.04
- neutropenia, severe congenital, 2, autosomal dominant · score 0.04
- nonimmune chronic idiopathic neutropenia of adults · score 0.04
- autosomal recessive severe congenital neutropenia due to CSF3R deficiency · score 0.04
- reticular dysgenesis · score 0.04
- pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 9 · score 0.04
- combined immunodeficiency with skin granulomas · score 0.04
- combined immunodeficiency due to moesin deficiency · score 0.04
- X-linked sideroblastic anemia 1 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95780-F1 | alphafold | PREDICTED | 69.86 | — |
Amino-acid sequence (498 residues)
MELLTFRDVT IEFSLEEWEF LNPAQQSLYR KVMLENYRNL VSLGLTVSKP ELISRLEQRQ EPWNVKRHET IAKPPAMSSH YTEDLLPEQC MQDSFQKVIL RRYGSCGLED LHLRKDGENV GECKDQKEIY NGLNQCLSTL PSKIFPYNKC VKVFSKSSNL NRENIRHTTE KLFKCMQCGK VFKSHSGLSY HKIIHTEEKL CICEECGKTF KWFSYLTKHK RIHTGEKPYK CEECGKAFNW CSSLTKHKRI HTGEKPYKCE ECGKAFHWCS PFVRHKKIHT GEKPYTCEDC GRAFNRHSHL TKHKTIHTGK KPYKCKECGK AFNHCSLLTI HERTHTGEKP YKCEECGKAF NSSSILTEHK VIHSGEKPYK CEKCDKVFKR FSYLTKHKRI HTGEKPYKCE ECGKAFNWSS ILTEHKRIHT GEKPYNCEEC GKAFNRCSHL TRHKKIHTAV KRYKCEECGK AFKRCSHLNE HKRVQRGEKS CKYKKCGEAF NHCSNLTT
Explore Zinc finger protein 682 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets