Caveolae-associated protein 2 (CAVIN2)

About Caveolae-associated protein 2

Caveolae-associated protein 2 (CAVIN2) is a protein from Homo sapiens identified by UniProt accession O95810, 425 residues long. MolForge cross-references it against 0 known binders and 128 disease associations.

Target properties

Protein name	Caveolae-associated protein 2
UniProt accession	O95810
Gene	CAVIN2
Organism	Homo sapiens
Length	425 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (128)

Diseases linked to this target (Open Targets).

mean platelet volume · score 0.64
platelet count · score 0.38
osteoarthritis, knee · score 0.31
PR interval · score 0.31
protein measurement · score 0.25
osteoarthritis, hip · score 0.25
risk-taking behaviour · score 0.09
lung adenocarcinoma · score 0.08
hepatocellular carcinoma · score 0.08
Pallister-Hall syndrome · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O95810-F1	alphafold	PREDICTED	62.88	—

Amino-acid sequence (425 residues)

MGEDAAQAEK FQHPGSDMRQ EKPSSPSPMP SSTPSPSLNL GNTEEAIRDN SQVNAVTVLT LLDKLVNMLD AVQENQHKME QRQISLEGSV KGIQNDLTKL SKYQASTSNT VSKLLEKSRK VSAHTRAVKE RMDRQCAQVK RLENNHAQLL RRNHFKVLIF QEENEIPASV FVKQPVSGAV EGKEELPDEN KSLEETLHTV DLSSDDDLPH DEEALEDSAE EKVEESRAEK IKRSSLKKVD SLKKAFSRQN IEKKMNKLGT KIVSVERREK IKKSLTSNHQ KISSGKSSPF KVSPLTFGRK KVREGESHAE NETKSEDLPS SEQMPNDQEE ESFAEGHSEA SLASALVEGE IAEEAAEKAT SRGSNSGMDS NIDLTIVEDE EEESVALEQA QKVRYEGSYA LTSEEAERSD GDPVQPAVLQ VHQTS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards