About Cerberus
Cerberus (CER1) is a protein
from Homo sapiens identified by UniProt accession
O95813, 267 residues long.
MolForge cross-references it against 0 known binders and
67 disease associations.
Target properties
| Protein name | Cerberus |
|---|
| UniProt accession | O95813 |
|---|
| Gene | CER1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 267 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (67)
Diseases linked to this target (Open Targets).
- body mass index · score 0.19
- self reported educational attainment · score 0.18
- body fat percentage · score 0.17
- DNA methylation · score 0.15
- hypertension · score 0.15
- age at first birth measurement · score 0.15
- bone density · score 0.14
- urate measurement · score 0.14
- cardiovascular disease · score 0.13
- waist circumference · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95813-F1 | alphafold | PREDICTED | 59.13 | — |
Amino-acid sequence (267 residues)
MHLLLFQLLV LLPLGKTTRH QDGRQNQSSL SPVLLPRNQR ELPTGNHEEA EEKPDLFVAV PHLVATSPAG EGQRQREKML SRFGRFWKKP EREMHPSRDS DSEPFPPGTQ SLIQPIDGMK MEKSPLREEA KKFWHHFMFR KTPASQGVIL PIKSHEVHWE TCRTVPFSQT ITHEGCEKVV VQNNLCFGKC GSVHFPGAAQ HSHTSCSHCL PAKFTTMHLP LNCTELSSVI KVVMLVEECQ CKVKTEHEDG HILHAGSQDS FIPGVSA
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