About Putative hydrolase DDAH2
Putative hydrolase DDAH2 (DDAH2) is a protein
from Homo sapiens identified by UniProt accession
O95865, 285 residues long.
MolForge cross-references it against 0 known binders and
169 disease associations.
Target properties
| Protein name | Putative hydrolase DDAH2 |
|---|
| UniProt accession | O95865 |
|---|
| Gene | DDAH2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 285 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (169)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.41
- blood protein measurement · score 0.14
- mosquito bite reaction size measurement · score 0.11
- cancer · score 0.08
- coronary artery disease · score 0.08
- Myocardial fibrosis · score 0.07
- neoplasm · score 0.06
- complement C4 measurement · score 0.05
- self reported educational attainment · score 0.05
- cognitive function measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95865-F1 | alphafold | PREDICTED | 92.71 | — |
Amino-acid sequence (285 residues)
MGTPGEGLGR CSHALIRGVP ESLASGEGAG AGLPALDLAK AQREHGVLGG KLRQRLGLQL LELPPEESLP LGPLLGDTAV IQGDTALITR PWSPARRPEV DGVRKALQDL GLRIVEIGDE NATLDGTDVL FTGREFFVGL SKWTNHRGAE IVADTFRDFA VSTVPVSGPS HLRGLCGMGG PRTVVAGSSD AAQKAVRAMA VLTDHPYASL TLPDDAAADC LFLRPGLPGV PPFLLHRGGG DLPNSQEALQ KLSDVTLVPV SCSELEKAGA GLSSLCLVLS TRPHS
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