Olfactory receptor 2H2 (OR2H2)

Homo sapiens — UniProt O95918

Gene: OR2H2Homo sapiensSwissProt reviewed

About Olfactory receptor 2H2

Olfactory receptor 2H2 (OR2H2) is a protein from Homo sapiens identified by UniProt accession O95918, 312 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein nameOlfactory receptor 2H2
UniProt accessionO95918
GeneOR2H2
OrganismHomo sapiens
Length312 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (25)

Diseases linked to this target (Open Targets).

  • thyroid gland adenocarcinoma · score 0.22
  • clear cell renal carcinoma · score 0.18
  • low grade glioma · score 0.18
  • prostate adenocarcinoma · score 0.18
  • serum alanine aminotransferase measurement · score 0.18
  • cervical carcinoma · score 0.14
  • female reproductive system disease · score 0.09
  • platelet count · score 0.05
  • psoriatic arthritis · score 0.04
  • unipolar depression · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-O95918-F1alphafoldPREDICTED89.11—

Amino-acid sequence (312 residues)

MVNQSSTPGF LLLGFSEHPG LERTLFVVVL TSYLLTLVGN TLIILLSALD PKLHSPMYFF LSNLSFLDLC FTTSCVPQML VNLWGPKKTI SFLDCSVQIF IFLSLGTTEC ILLTVMAFDR YVAVCQPLHY ATIIHPRLCW QLASVAWVIG LVESVVQTPS TLHLPFCPDR QVDDFVCEVP ALIRLSCEDT SYNEIQVAVA SVFILVVPLS LILVSYGAIT WAVLRINSAK GRRKAFGTCS SHLTVVTLFY SSVIAVYLQP KNPYAQERGK FFGLFYAVGT PSLNPLIYTL RNKEVTRAFR RLLGKEMGLT QS

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Quick facts

UniProtO95918
GeneOR2H2
OrganismHomo sapiens
Length312
Binders0
Diseases25
View on UniProt