About Olfactory receptor 2H2
Olfactory receptor 2H2 (OR2H2) is a protein
from Homo sapiens identified by UniProt accession
O95918, 312 residues long.
MolForge cross-references it against 0 known binders and
25 disease associations.
Target properties
| Protein name | Olfactory receptor 2H2 |
| UniProt accession | O95918 |
| Gene | OR2H2 |
| Organism | Homo sapiens |
| Length | 312 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.22
- clear cell renal carcinoma · score 0.18
- low grade glioma · score 0.18
- prostate adenocarcinoma · score 0.18
- serum alanine aminotransferase measurement · score 0.18
- cervical carcinoma · score 0.14
- female reproductive system disease · score 0.09
- platelet count · score 0.05
- psoriatic arthritis · score 0.04
- unipolar depression · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-O95918-F1 | alphafold | PREDICTED | 89.11 | — |
Amino-acid sequence (312 residues)
MVNQSSTPGF LLLGFSEHPG LERTLFVVVL TSYLLTLVGN TLIILLSALD PKLHSPMYFF LSNLSFLDLC FTTSCVPQML VNLWGPKKTI SFLDCSVQIF IFLSLGTTEC ILLTVMAFDR YVAVCQPLHY ATIIHPRLCW QLASVAWVIG LVESVVQTPS TLHLPFCPDR QVDDFVCEVP ALIRLSCEDT SYNEIQVAVA SVFILVVPLS LILVSYGAIT WAVLRINSAK GRRKAFGTCS SHLTVVTLFY SSVIAVYLQP KNPYAQERGK FFGLFYAVGT PSLNPLIYTL RNKEVTRAFR RLLGKEMGLT QS
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