About Chromobox protein homolog 7
Chromobox protein homolog 7 (CBX7) is a protein
from Homo sapiens identified by UniProt accession
O95931, 251 residues long.
MolForge cross-references it against 0 known binders and
142 disease associations.
Target properties
| Protein name | Chromobox protein homolog 7 |
| UniProt accession | O95931 |
| Gene | CBX7 |
| Organism | Homo sapiens |
| Length | 251 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (142)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.42
- leukocyte count · score 0.39
- neutrophil count · score 0.39
- erythrocyte count · score 0.36
- hemoglobin measurement · score 0.34
- red blood cell density measurement · score 0.33
- body height · score 0.33
- multiple myeloma · score 0.32
- hematocrit · score 0.30
- myeloid white cell count · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-O95931-F1 | alphafold | PREDICTED | 66.22 | — |
Amino-acid sequence (251 residues)
MELSAIGEQV FAVESIRKKR VRKGKVEYLV KWKGWPPKYS TWEPEEHILD PRLVMAYEEK EERDRASGYR KRGPKPKRLL LQRLYSMDLR SSHKAKGKEK LCFSLTCPLG SGSPEGVVKA GAPELVDKGP LVPTLPFPLR KPRKAHKYLR LSRKKFPPRG PNLESHSHRR ELFLQEPPAP DVLQAAGEWE PAAQPPEEEA DADLAEGPPP WTPALPSSEV TVTDITANSI TVTFREAQAA EGFFRDRSGK F
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