Chromobox protein homolog 7 (CBX7)

Homo sapiens — UniProt O95931

Gene: CBX7Homo sapiensSwissProt reviewed

About Chromobox protein homolog 7

Chromobox protein homolog 7 (CBX7) is a protein from Homo sapiens identified by UniProt accession O95931, 251 residues long. MolForge cross-references it against 0 known binders and 142 disease associations.

Target properties

Protein nameChromobox protein homolog 7
UniProt accessionO95931
GeneCBX7
OrganismHomo sapiens
Length251 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (142)

Diseases linked to this target (Open Targets).

  • lymphocyte count · score 0.42
  • leukocyte count · score 0.39
  • neutrophil count · score 0.39
  • erythrocyte count · score 0.36
  • hemoglobin measurement · score 0.34
  • red blood cell density measurement · score 0.33
  • body height · score 0.33
  • multiple myeloma · score 0.32
  • hematocrit · score 0.30
  • myeloid white cell count · score 0.29

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-O95931-F1alphafoldPREDICTED66.22—

Amino-acid sequence (251 residues)

MELSAIGEQV FAVESIRKKR VRKGKVEYLV KWKGWPPKYS TWEPEEHILD PRLVMAYEEK EERDRASGYR KRGPKPKRLL LQRLYSMDLR SSHKAKGKEK LCFSLTCPLG SGSPEGVVKA GAPELVDKGP LVPTLPFPLR KPRKAHKYLR LSRKKFPPRG PNLESHSHRR ELFLQEPPAP DVLQAAGEWE PAAQPPEEEA DADLAEGPPP WTPALPSSEV TVTDITANSI TVTFREAQAA EGFFRDRSGK F

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Quick facts

UniProtO95931
GeneCBX7
OrganismHomo sapiens
Length251
Binders0
Diseases142
View on UniProt