About Eomesodermin homolog
Eomesodermin homolog (EOMES) is a protein
from Homo sapiens identified by UniProt accession
O95936, 686 residues long.
MolForge cross-references it against 0 known binders and
231 disease associations.
Target properties
| Protein name | Eomesodermin homolog |
|---|
| UniProt accession | O95936 |
|---|
| Gene | EOMES |
|---|
| Organism | Homo sapiens |
|---|
| Length | 686 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (231)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- eosinophil count · score 0.46
- leukocyte count · score 0.44
- lymphocyte count · score 0.43
- rheumatoid arthritis · score 0.43
- multiple sclerosis · score 0.40
- mean corpuscular volume · score 0.39
- platelet count · score 0.39
- chronic lymphocytic leukemia · score 0.39
- basophil count · score 0.38
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95936-F1 | alphafold | PREDICTED | 55.21 | — |
Amino-acid sequence (686 residues)
MQLGEQLLVS SVNLPGAHFY PLESARGGSG GSAGHLPSAA PSPQKLDLDK ASKKFSGSLS CEAVSGEPAA ASAGAPAAML SDTDAGDAFA SAAAVAKPGP PDGRKGSPCG EEELPSAAAA AAAAAAAAAA TARYSMDSLS SERYYLQSPG PQGSELAAPC SLFPYQAAAG APHGPVYPAP NGARYPYGSM LPPGGFPAAV CPPGRAQFGP GAGAGSGAGG SSGGGGGPGT YQYSQGAPLY GPYPGAAAAG SCGGLGGLGV PGSGFRAHVY LCNRPLWLKF HRHQTEMIIT KQGRRMFPFL SFNINGLNPT AHYNVFVEVV LADPNHWRFQ GGKWVTCGKA DNNMQGNKMY VHPESPNTGS HWMRQEISFG KLKLTNNKGA NNNNTQMIVL QSLHKYQPRL HIVEVTEDGV EDLNEPSKTQ TFTFSETQFI AVTAYQNTDI TQLKIDHNPF AKGFRDNYDS SHQIVPGGRY GVQSFFPEPF VNTLPQARYY NGERTVPQTN GLLSPQQSEE VANPPQRWLV TPVQQPGTNK LDISSYESEY TSSTLLPYGI KSLPLQTSHA LGYYPDPTFP AMAGWGGRGS YQRKMAAGLP WTSRTSPTVF SEDQLSKEKV KEEIGSSWIE TPPSIKSLDS NDSGVYTSAC KRRRLSPSNS SNENSPSIKC EDINAEEYSK DTSKGMGGYY AFYTTP
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