About Immunoglobulin superfamily member 6
Immunoglobulin superfamily member 6 (IGSF6) is a protein
from Homo sapiens identified by UniProt accession
O95976, 241 residues long.
MolForge cross-references it against 0 known binders and
53 disease associations.
Target properties
| Protein name | Immunoglobulin superfamily member 6 |
|---|
| UniProt accession | O95976 |
|---|
| Gene | IGSF6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 241 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (53)
Diseases linked to this target (Open Targets).
- balding measurement · score 0.16
- hair shape measurement · score 0.15
- unipolar depression · score 0.09
- neoplasm · score 0.09
- lung adenocarcinoma · score 0.08
- major depressive disorder · score 0.05
- clear cell renal carcinoma · score 0.03
- lung carcinoma · score 0.02
- drug use measurement · score 0.02
- Acute hepatic failure · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95976-F1 | alphafold | PREDICTED | 79.57 | — |
Amino-acid sequence (241 residues)
MGTASRSNIA RHLQTNLILF CVGAVGACTL SVTQPWYLEV DYTHEAVTIK CTFSATGCPS EQPTCLWFRY GAHQPENLCL DGCKSEADKF TVREALKENQ VSLTVNRVTS NDSAIYICGI AFPSVPEARA KQTGGGTTLV VREIKLLSKE LRSFLTALVS LLSVYVTGVC VAFILLSKSK SNPLRNKEIK EDSQKKKSAR RIFQEIAQEL YHKRHVETNQ QSEKDNNTYE NRRVLSNYER P
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