Actin-associated protein FAM107A (FAM107A)

About Actin-associated protein FAM107A

Actin-associated protein FAM107A (FAM107A) is a protein from Homo sapiens identified by UniProt accession O95990, 144 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.

Target properties

Protein name	Actin-associated protein FAM107A
UniProt accession	O95990
Gene	FAM107A
Organism	Homo sapiens
Length	144 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (85)

Diseases linked to this target (Open Targets).

neoplasm · score 0.09
cancer · score 0.08
neuroblastoma · score 0.06
non-small cell lung carcinoma · score 0.05
urinary bladder carcinoma · score 0.04
breast carcinoma · score 0.04
autoimmune thrombocytopenic purpura · score 0.04
protein measurement · score 0.04
lung adenocarcinoma · score 0.03
hemolytic anemia · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O95990-F1	alphafold	PREDICTED	75.13	—

Amino-acid sequence (144 residues)

MYSEIQRERA DIGGLMARPE YREWNPELIK PKKLLNPVKA SRSHQELHRE LLMNHRRGLG VDSKPELQRV LEHRRRNQLI KKKKEELEAK RLQCPFEQEL LRRQQRLNQL EKPPEKEEDH APEFIKVREN LRRIATLTSE EREL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards