About Protein phosphatase 1 regulatory subunit 17
Protein phosphatase 1 regulatory subunit 17 (PPP1R17) is a protein
from Homo sapiens identified by UniProt accession
O96001, 155 residues long.
MolForge cross-references it against 0 known binders and
28 disease associations.
Target properties
| Protein name | Protein phosphatase 1 regulatory subunit 17 |
|---|
| UniProt accession | O96001 |
|---|
| Gene | PPP1R17 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 155 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (28)
Diseases linked to this target (Open Targets).
- PHF-tau measurement · score 0.16
- psoriasis · score 0.11
- female reproductive system disease · score 0.10
- metabolite measurement · score 0.09
- FEV/FVC ratio · score 0.08
- protein measurement · score 0.05
- neurofibrillary tangles measurement · score 0.04
- Blackfan-Diamond anemia · score 0.04
- neutropenia, severe congenital, 2, autosomal dominant · score 0.04
- Recurrent infection due to specific granule deficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O96001-F1 | alphafold | PREDICTED | 66.37 | — |
Amino-acid sequence (155 residues)
MMSTEQMQPL ELSEDRLDKL DPRCSHLDDL SDQFIKDCDL KKKPRKGKNV QATLNVESDQ KKPRRKDTPA LHIPPFIPGV FSEHLIKRYD VQERHPKGKM IPVLHNTDLE QKKPRRKDTP ALHMSPFAAG VTLLRDERPK AIVEDDEKDG DKIAI
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